| 产品详情 |
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| Antigenic Specificity | NOX2/gp91phox |
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| Clone | 54.1 |
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| Host Species | Mouse |
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| Reactive Species | human |
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| Isotype | IgG1 |
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| Format | peroxidase (HRP) conjugate |
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| Size | 50ul |
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| Concentration | 1mg/ml |
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| Applications | IHC-P, WB |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Mouse Anti-NOX2/gp91phox [54.1]: Horseradish Peroxidase (HRP). This antibody recognises Cytochrome b-245 heavy chain (CYBB), which is also know as NOX2/gp91phox. NOX2/gp91phox is a component of the membrane-bound oxidase of phagocytes that generates superoxide. Defects in the CYBB gene are a cause of Chronic X-linked granulomatous disease (CGD). This antibody is specific for NOX2/gp91phox 382-PKIAVDGP-389 |
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| Immunogen | Partially Purified human neutrophil flavocytochrome b (heparin Ultrogellectin affinity purification in Triton X-100) |
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| Other Names | CGD91-phox, CYBB, Cytochrome b(558) beta chain, Cytochrome b-245 heavychain, gp91-1, gp91-phox, Heme-binding membrane glycoprotein gp91phox, NADPHoxidase 2, Neutrophil cytochrome b 91 kDa polypeptide, NOX2, p22 phagocyte B-cytochrome; Superoxide-generating NADPH oxidase heavy chain subunit |
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| Gene, Accession # | n/a |
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| Catalog # | IQ439HRP |
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| Price | |
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| Order / More Info | NOX2/gp91phox Antibody from IMMUQUEST LTD. |
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| Product Specific References | Baniulis D et al. Evaluation of two anti-gp91phox antibodies as immunoprobes for Nox family proteins: mAb 54.1 recognizes recombinant full-length Nox2, Nox3 and the C-terminal domains of Nox1-4 and cross-reacts with GRP 58. Biochim Biophys Acta 1752:186-96 (2005) PUBMED Burritt JB et al. Topological mapping of neutrophil cytochrome b epitopes with phage-display libraries. J Biol Chem 270:16974-80 (1995) PUBMED |
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