| 产品详情 |
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| Antigenic Specificity | HEXA |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human, mouse, rat |
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| Isotype | n/a |
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| Format | immunogen affinity purified |
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| Size | 100µg |
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| Concentration | n/a |
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| Applications | ELISA, WB, IHC • WB 1:500 - 1:2000; IHC 1:50 - 1:200 |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Rabbit anti-HEXA polyclonal antibody. This gene encodes a member of the glycosyl hydrolase 20 family of proteins. The encoded preproprotein is proteolytically processed to generate the alpha subunit of the lysosomal enzyme beta-hexosaminidase. This enzyme, together with the cofactor GM2 activator protein, catalyzes the degradation of the ganglioside GM2, and other molecules containing terminal N-acetyl hexosamines. Mutations in this gene lead to an accumulation of GM2 ganglioside in neurons, the underlying cause of neurodegenerative disorders termed the GM2 gangliosidoses, including Tay-Sachs disease (GM2-gangliosidosis type I). Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that |
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| Immunogen | hexosaminidase A (alpha polypeptide) |
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| Other Names | n/a |
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| Gene, Accession # | Gene ID: 3073, UniProt: P06865 |
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| Catalog # | FNab03842 |
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| Price | |
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| Order / More Info | HEXA Antibody from FINETEST |
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| Product Specific References | n/a |
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