| 产品详情 |
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| Antigenic Specificity | MDC1 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human |
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| Isotype | n/a |
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| Format | immunogen affinity purified |
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| Size | 100µg |
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| Concentration | n/a |
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| Applications | ELISA, IHC, IF • WB 1:500 - 1:2000; IHC 1:100 - 1:200 |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Rabbit anti-MDC1 polyclonal antibody. The protein encoded by this gene contains an N-terminal forkhead domain, two BRCA1 C-terminal (BRCT) motifs and a central domain with 13 repetitions of an approximately 41-amino acid sequence. The encoded protein is required to activate the intra-S phase and G2/M phase cell cycle checkpoints in response to DNA damage. This nuclear protein interacts with phosphorylated histone H2AX near sites of DNA double-strand breaks through its BRCT motifs, and facilitates recruitment of the ATM kinase and meiotic recombination 11 protein complex to DNA damage foci. |
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| Immunogen | mediator of DNA damage checkpoint 1 |
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| Other Names | KIAA0170, NFBD1 |
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| Gene, Accession # | Gene ID: 9656, UniProt: Q14676 |
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| Catalog # | FNab05072 |
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| Price | |
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| Order / More Info | MDC1 Antibody from FINETEST |
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| Product Specific References | n/a |
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| 产品资料 |
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