| 产品详情 |
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| Antigenic Specificity | MLH1 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human, mouse, rat |
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| Isotype | n/a |
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| Format | Alexa Fluor® 647 conjugate |
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| Size | 100ul |
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| Concentration | 1ug/ul |
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| Applications | IF(IHC-P) |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | MLH1 Polyclonal Antibody, Alexa Fluor® 647 Conjugated. • Target Background: Heterodimerizes with PMS2 to form MutL alpha, a component of the post-replicative DNA mismatch repair system (MMR). DNA repair is initiated by MutS alpha (MSH2-MSH6) or MutS beta (MSH2-MSH6) binding to a dsDNA mismatch, then MutL alpha is recruited to the heteroduplex. Assembly of the MutL-MutS-heteroduplex ternary complex in presence of RFC and PCNA is sufficient to activate endonuclease activity of PMS2. It introduces single-strand breaks near the mismatch and thus generates new entry points f |
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| Immunogen | KLH conjugated synthetic peptide derived from human MLH1. Immunogen Range: 520-570/756 |
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| Other Names | FCC2; COCA2; HNPCC; hMLH1; HNPCC2; DNA mismatch repair protein Mlh1; MutL protein homolog 1; MLH1 |
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| Gene, Accession # | Gene ID: 4292, SwissProt: P40692 |
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| Catalog # | bs-0836R-A647 |
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| Price | |
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| Order / More Info | MLH1 Antibody from BIOSS ANTIBODIES |
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| Product Specific References | n/a |
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| 产品资料 |
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