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| Product Name | Cytochrome P450 2D6 Fluorometric Activity Assay Kit |
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| Description | CYP2D6 Activity Assay Kit enables rapid measurement of native or recombinant CYP2D6 activity in biological samples such as liver microsomes. The assay utilizes a non-fluorescent CYP2D6-selective substrate that is converted into a highly fluorescent metabolite detected in the visible range (Ex/Em = 390/468 nm), ensuring a high signal-to-background ratio with little interference by autofluorescence. CYP2D6 specific activity is calculated by running parallel reactions in the presence and absence of the potent CYP2D6-selective inhibitor quinidine and subtracting any residual activity detected with the inhibitor present. The kit contains a complete set of reagents sufficient for performing 100 sets of paired reactions (in the presence and absence of inhibitor). |
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| Size | 200 assays |
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| Concentration | n/a |
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| Applications | Rapid assessment of native/recombinant CYP2D6 activity in lysates or microsomal fractions prepared from tissues or cells. Screening of drugs and novel ligands for interaction with native/recombinant CYP2D6. |
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| Other Names | n/a |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | Kit-2134 |
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| Order / More Info | Cytochrome P450 2D6 Fluorometric Activity Assay Kit from CREATIVE BIOMART |
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| Product Specific References | n/a |
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