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| Product Name | Cholesterol Detection Kit (cell-based) |
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| Description | Cholesterol is an essential structural component of animal cell membranes. It is required to maintain membrane structural integrity and fluidity. Cholesterol also serves as a precursor for the biosynthesis of several hormones, bile acid and vitamin D. Plasma membrane contains majority of the cellular cholesterol (80-90%) whereas little cholesterol resides in endoplasmic reticulum and in mitochondrial membrane. Transport of intracellular cholesterol within the cells to different compar;ents is through vesicular and non-vesicular pathways. Defects in these transport processes can alter cellular cholesterol metabolism resulting in pathological conditions. Filipin III is widely used as a probe for sterol localization in membranes. Interaction with cholesterol alters Filipin absorption and fluorescence spectra. This assay provides a simple, easy to perform, histochemical method of identification of unesterified cholesterol. |
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| Size | 100 assays |
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| Concentration | n/a |
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| Applications | Screen/study/characterize stimulators/inhibitors that affect cholesterol transport and localization in a variety of cells. |
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| Other Names | n/a |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | Kit-2317 |
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| Order / More Info | Cholesterol Detection Kit (cell-based) from CREATIVE BIOMART |
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| Product Specific References | n/a |
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