| 产品详情 |
| Edit |   |
|---|
| Product Name | Montelukast (sodium salt) |
|---|
| Description | The CysLTs, LTC4 and LTD4, are potent mediators of asthma and hypersensitivity. They induce bronchoconstriction, increase microvascular permeability, and are vasoconstrictors of coronary arteries. Their biological effects are transduced by a pair of GPCRs, CysLT1 and CysLT2.{7174,8519,14081} Montelukast (sodium salt) is a potent, selective CysLT1 receptor antagonist sold under the trade name Singulair for the treatment of asthma as well as for the symptoms associated with allergic rhinitis.{6475,6685,14084,14106} It binds to the human CysLT1 receptor with an IC50 of less than 5 nM with no appreciable binding to the CysLT2 receptor.{7174,8519,14081} |
|---|
| Size | 50 mg |
|---|
| Concentration | n/a |
|---|
| Applications | n/a |
|---|
| Other Names | ?MK-476 |
|---|
| Gene, Accession, CAS # | CAS: 151767-02-1 |
|---|
| Catalog # | 10008318-50 |
|---|
| Price | |
|---|
| Order / More Info | Montelukast (sodium salt) from CAYMAN CHEMICAL COMPANY |
|---|
| Product Specific References | n/a |
|---|
| 产品资料 |
|
|