| 产品详情 |
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| Product Name | (±)-Gossypol |
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| Description | Isolated from cotton seeds. It causes infertility in a variety of cotton pests and spermatogenesis arrest in humans. Gossypol also has antimalarial properties, preventing the growth of P. falciparum at low micromolar concentrations. It inhibits aldose reductase (Ki = 0.5 µM).Gossypol also acts as an anticancer agent, inhibiting cell growth in various cancer cell lines, in part by blocking the anti-apoptotic functions of Bcl-2 and Bcl-xL, again at low micromolar concentrations. Also acts as a non-selective competitive inhibitor of NADH binding to LDH, with K(i) values of 1.9, 1.4, and 4.2 µM for LDH-A4, -B4, and -C4, respectively. MW: 518.55. Purity ≥95% |
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| Size | 250 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | (±)-2,2?-bis(8-Formyl-1,6,7-trihydroxy-5-isopropyl-3-methylnaphthalene; NSC 56817; NSC 524336; BL 193; Pogosin |
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| Gene, Accession, CAS # | CAS: 303-45-7 |
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| Catalog # | 2579-250 |
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| Price | |
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| Order / More Info | (±)-Gossypol from BIOVISION, INC. |
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| Product Specific References | n/a |
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