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| Product Name | Cytochrome P450 2D6, human recombinant |
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| Description | Cytochrome P450 2D6 is a member of a family of microsomal enzymes (mono-oxygenases) present in the endoplasmic reticulum membrane, which detoxify xenobiotic compounds. Cytochrome P450 2D6 is the molecular target of autoantibodies against the liver kidney microsomal antigen 1 (LKM 1) which has been classically studied by immunofluorescence microscopy. The presence of these autoantibodies is considered indicative of Autoimmune Hepatitis Type 2; LKM 1 antibodies have also been detected in patients with hepatitis C viral infection. The use of a purified recombinant Cytochrome P450 2D6 antigen allows the differentiation of autoimmune hepatitis from drug-induced hepatitis where transient autoantibodies to other P450 family members occur which c |
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| Size | 20 µg |
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| Concentration | Lot specific |
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| Applications | RUO |
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| Other Names | Cytochrome P450 2D6, CYPIID6, P450-DB1, Debrisoquine 4-hydroxylase, CYP2D6, CPD6, CYP2D, CYP2DL1, P450C2D, MGC120389, MGC120390, LKM1, liver/kidney microsomal antigen 1 |
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| Gene, Accession, CAS # | CYP2D6, Gene ID: 1565, Accession: P10635 |
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| Catalog # | 7870-20 |
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| Order / More Info | Cytochrome P450 2D6, human recombinant from BIOVISION, INC. |
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| Product Specific References | n/a |
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