| 产品详情 |
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| Product Name | AZ-3146 |
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| Description | AZ 3146 is a potent and selective Mps1 (monopolar spindle 1) kinase inhibitor (IC50 = 35 nM). Shows selectivity over 46 other kinases including aurora kinase B and Cdk1. AZ 3146 overrides spindle assembly checkpoint and also interferes with chromosome alignment. It has shown to inhibit the recruitment of Mad1, 2 and centromere protein E (CENP-E) to kinetochores. MW: 452.55. Purity ≥98% by HPLC |
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| Size | 5 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 9-Cyclopentyl-2-[[2-methoxy-4-[(1-methylpiperidin-4-yl)oxy]-phenyl]amino]-7-methyl-7,9-dihydro-8H-purin-8-one |
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| Gene, Accession, CAS # | CAS: 1124329-14-1 |
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| Catalog # | B1145-5 |
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| Order / More Info | AZ-3146 from BIOVISION, INC. |
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| Product Specific References | n/a |
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