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Product Name | AZ-5104 |
Description | AZ-5104 is an active, demethylated metabolite of AZD-9291 (Cat.No.2674). It displays similar overall activity profile with AZD-9291, but is more potent against mutant EGFR forms, while hitting the wild-type EGFR form at a lower concentration thus demonstrating a smaller selectivity margin compared with the parent. Like AZD-9291, AZ-5104 displays potent antitumor activities both in vitro and in vivo. MW: 485.58. Purity ≥98% by HPLC |
Size | 10 mg |
Concentration | n/a |
Applications | n/a |
Other Names | N-(5-((4-(1H-indol-3-yl)pyrimidin-2-yl)amino)-2-((2-(dimethylamino)ethyl)(methyl)amino)-4-methoxyphenyl)acrylamide |
Gene, Accession, CAS # | CAS: 1421373-98-9 |
Catalog # | 9441-10 |
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Order / More Info | AZ-5104 from BIOVISION, INC. |
Product Specific References | n/a |
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