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| Product Name | 11-deoxy-11-methylene-15-keto Prostaglandin D2 |
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| Description | PGD2 is one of the five primary enzymatic prostaglandins derived directly from PGH2. Many of the biological effects of PGD2 are transduced in vivo by a classical 7-transmembrane GPCR, the DP1 receptor.{3128} However, a second receptor, the chemokine-related CRTH2 receptor, also binds PGD2.{10058,10722} This new receptor was recently identified on human eosinophils, where it binds selectively the PGD2 metabolite 13,14-dihydro-15-keto PGD2.{9769} 11-deoxy-11-methylene-15-keto PGD2 was prepared as a more chemically stable ligand for this receptor. There are no published studies of the pharmacological properties of 11-deoxy-11-methylene-15-keto PGD2. |
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| Size | 500 µg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 11-deoxy-11-methylene-15-keto PGD2 |
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| Gene, Accession, CAS # | CAS: 958759-75-6 |
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| Catalog # | 12415-500 |
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| Order / More Info | 11-deoxy-11-methylene-15-keto Prostaglandin D2 from CAYMAN CHEMICAL COMPANY |
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| Product Specific References | n/a |
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