产品名称 TNF-alpha, Human Antibody from HYCULT BIOTECH
产品货号 HM2010
产品价格 现货询价,电话:010-67529703
产品规格 100 µg
产品品牌 HYCULT BIOTECH
产品概述
产品详情
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Antigenic SpecificityTNF-alpha, Human
Clone52B83
Host SpeciesMouse
Reactive Specieshuman, guinea pig, mouse, rhesus monkey
IsotypeIgG1
Formatunconjugated
Size100 µg
Concentration100 µg/ml
Applicationsfrozen sections, FC, immunoassay, WB
Reviews / RatingsIf you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY.
DescriptionThe monoclonal antibody 52B83 reacts with tumor necrosis factor alpha (TNF-alpha). TNF-alpha is a homotrimeric 17 kDa protein, that interacts with either one of the two types of TNF-receptors, termed I and II, leading to receptor cross-linking and signal transduction. The receptors differ strongly in their intra-cellular signaling pathways. TNF-alpha was originally described as a highly cytotoxic cytokine for tumor cells, it causes tumor necrosis in vivo and shows cytolytic activity against tumor cells in vitro. Furthermore,- TNF-alpha is found to be a central mediator in many inflammatory and immunological processes. It can be induced by various products of micro-organisms and by various cytokines leading to expression of a wide variety of- cytokines. The pro-inflammatory properties of- TNF-alpha play a central role in several auto-immune diseases such as rheumatoid arthritis and inhibition by neutralizing molecules have been shown to be beneficial in patients.
Immunogenn/a
Other NamesTumor Necrosis Factor-alpha, TNF, TNF-SF2, cachectin
Gene, Accession #n/a
Catalog #HM2010
Price
Order / More InfoTNF-alpha, Human Antibody from HYCULT BIOTECH
Product Specific Referencesn/a
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