| 产品详情 |
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| Antigenic Specificity | SSRP1 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human, mouse |
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| Isotype | n/a |
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| Format | immunogen affinity purified |
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| Size | 100µg |
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| Concentration | n/a |
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| Applications | ELISA, WB, IHC, IP • WB 1:500 - 1:2000; IHC 1:50 - 1:200; IF 1:10 - 1:100 |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Rabbit anti-SSRP1 polyclonal antibody. The protein encoded by this gene is a subunit of a heterodimer that, along with SUPT16H, forms chromatin transcriptional elongation factor FACT. FACT interacts specifically with histones H2A/H2B to effect nucleosome disassembly and transcription elongation. FACT and cisplatin-damaged DNA may be crucial to the anticancer mechanism of cisplatin. This encoded protein contains a high mobility group box which most likely constitutes the structure recognition element for cisplatin-modified DNA. This protein also functions as a co-activator of the transcriptional activator p63. An alternatively spliced transcript variant of this gene has been described, but its full-length nature is not known. |
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| Immunogen | structure specific recognition protein 1 |
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| Other Names | FACT80 |
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| Gene, Accession # | Gene ID: 6749, UniProt: Q08945 |
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| Catalog # | FNab08250 |
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| Price | |
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| Order / More Info | SSRP1 Antibody from FINETEST |
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| Product Specific References | n/a |
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