| 产品详情 |
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| Antigenic Specificity | BRCA1 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human, mouse |
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| Isotype | n/a |
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| Format | immunogen affinity purified |
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| Size | 100µg |
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| Concentration | n/a |
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| Applications | ELISA, WB, IHC, IP • WB 1:500 - 1:2000; IHC 1:50 - 1:200; IF 1:20 - 1:50 |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Rabbit anti-BRCA1 polyclonal antibody. This gene encodes a nuclear phosphoprotein that plays a role in maintaining genomic stability, and it also acts as a tumor suppressor. The encoded protein combines with other tumor suppressors, DNA damage sensors, and signal transducers to form a large multi-subunit protein complex known as the BRCA1-associated genome surveillance complex (BASC). This gene product associates with RNA polymerase II, and through the C-terminal domain, also interacts with histone deacetylase complexes. This protein thus plays a role in transcription, DNA repair of double-stranded breaks, and recombination. Mutations in this gene are responsible for approximately 40% of inherited breast cancers and more than 80% of inherit |
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| Immunogen | breast cancer 1, early onset |
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| Other Names | RNF53 |
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| Gene, Accession # | Gene ID: 672, UniProt: P38398 |
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| Catalog # | FNab00942 |
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| Price | |
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| Order / More Info | BRCA1 Antibody from FINETEST |
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| Product Specific References | n/a |
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