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| Antigenic Specificity | Neurotrophic tyrosine Kinase, Receptor, Type 3 (NTRK3) (pTyr820) |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | rat, mouse, human |
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| Isotype | n/a |
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| Format | unconjugated |
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| Size | 500 µg |
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| Concentration | n/a |
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| Applications | Immunohistochemistry (IHC),Western Blotting (WB) |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Function: Receptor for neurotrophin-3 (NT-3). This is a tyrosine-protein kinase receptor. Known substrates for the trk receptors are SHC1, PI-3 kinase, and PLCG1. The different isoforms do not have identical signaling properties.Catalytic activity: ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate.Subunit: Exists in a dynamic equilibrium between monomeric (low affinity) and dimeric (high affinity) structures. Binds SH2B2. Interacts with SQSTM1 and ARMS.Subcellular location: Membrane, Single-pass type I membrane protein.Tissue specificity: Widely expressed, mainly in the nervous tissue. The isoform B is expressed in a relatively large amount in the adult brain comparatively to fetal brain. Also known as: Neurotrophic tyrosine kinase receptor type 3, TrkC tyrosine kinase, GP145-TrkC, Trk-C, NT-3 growth factor receptor, NTRK3. |
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| Immunogen | A synthetic peptide to phospho Y820 of human TrkC conjugated to blue carrier protein was used as the antigen. The antigen is homologous in rat and mouse. The peptide is homologous in rat and mouse. |
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| Other Names | TRKC|gp145(trkC)|AW125844|Ntrk3_tv3|TrkC|trkC |
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| Gene, Accession # | Gene ID: 4916,18213,29613 |
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| Catalog # | ABIN350739 |
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| Order / More Info | Neurotrophic tyrosine Kinase, Receptor, Type 3 (NTRK3) (pTyr820) Antibody from ANTIBODIES-ONLINE GmbH |
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| Product Specific References | PubMed: 18034455, 7806211, 1488112, 9856458, 7823156, 10388563, 8494648, 8494647 |
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