| 产品详情 |
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| Antigenic Specificity | Human SELE |
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| Clone | FOB2 |
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| Host Species | Mouse |
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| Reactive Species | human, baboon, chimpanzee, cynomolgus monkey, rhesus monkey. |
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| Isotype | IgG1 |
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| Format | unconjugated |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | IP, IA, IHC-F |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Mouse Anti-Human SELE monoclonal antibody for IP, IA, IHC-F. CD62E is also known as endothelial leukocyte adhesion molecule 1 (ELAM1) or E selectin. It is a type I membrane protein that belongs to the selectin family of surface molecules (along with CD62L and CD62P). Selectins are C type cell surface lectins that play a role in leukocyte adhesion to the blood vessel wall endothelium. CD62E (E selectin) is an endothelial cell specific selectin that is expressed on cytokine induced endothelial cells only after activation with proinflammatory cytokines. In vitro experiments have shown that IL1, TNFalpha and bacterial wall components like lipopolysaccharides induce the transcription of CD62E in an NFkB dependent signalling cascade. CD62E has been associated with blood vessel endothelium in diverse inflammatory situations. The main ligands recognised by CD62E are oligosaccharides related to sialyl lewis x. |
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| Immunogen | CD62E / E-Selectin protein |
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| Other Names | CD62 antigen-like family member E, ELAM1, Endothelial leukocyte adhesion molecule 1, LECAM2, Leukocyte-endothelial cell adhesion molecule 2, SELE |
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| Gene, Accession # | Gene ID: 6401, UniProt: P16581 |
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| Catalog # | CABT-L1123 |
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| Price | |
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| Order / More Info | Human SELE Antibody from CREATIVE DIAGNOSTICS |
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| Product Specific References | n/a |
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