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| Product Name | IMPDH2, 1-514aa, Human, His tag, E Coli |
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| Description | MW: 58.0kDa (534aa). Purity >90% by SDS-PAGE. IMPDH2 belongs to the IMPDH/GMPR family. It catalyzes the NAD-dependent oxidation of inosine-5'-monophosphate into xanthine-5'-monophosphate, which is then converted into guanosine-5'-monophosphate. IMPDH2 is the rate-limiting enzyme in the de novo guanine nucleotide biosynthesis. It is thus involved in maintaining cellular guanine deoxy- and ribonucleotide pools needed for DNA and RNA synthesis. Also IMPDH1 and IMPDH2 are targets for the important i |
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| Size | 0.05 mg, 0.25 mg |
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| Concentration | 0.5 mg/ml (determined by Bradford assay) |
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| Applications | SDS-PAGE |
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| Other Names | [Inosine-5'-monophosphate dehydrogenase 2; IMPD2; IMPDH-II] |
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| Gene, Accession, CAS # | IMPDH2, Gene ID: 3615, Accession: NP_000875 |
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| Catalog # | MBS204353 |
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| Order / More Info | IMPDH2, 1-514aa, Human, His tag, E Coli from MYBIOSOURCE INC. |
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| Product Specific References | Wu TY, Peng Y, et al. (2010) Pharmacol. 161 (7):1584-98. ; Bremer S, et al. (2008) Transplantation. 85 (1):55-61. |
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