产品详情 |
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Antigenic Specificity | BCR |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 100 ul, 50 ul, 200 ul |
Concentration | n/a |
Applications | IHC-P, WB |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Rabbit polyclonal antibody to BCR. The breakpoint cluster region protein (Bcr) is best know to be involved in genomic translocation with fusion partner Abl (Cbr-Abl) causing chronic myelogenous leukemia (CML). This 160 kDa protein contains a serine/threonine kinase domain, an SH2 binding domain, a GTP/GDP exchange domain and a C-term domain which functions as a GTPase activating protein for p21rac and CDC42. Additionally, Bcr is involved in signal transduction and can down regulate Ras mediated cell signaling. |
Immunogen | Recombinant protein of human BCR |
Other Names | ALL, BCR1, CML, D22S11, D22S662, PHL, Breakpoint cluster region protein, Renal carcinoma antigen NY-REN-26 |
Gene, Accession # | Gene ID: 613, UniProt: P11274 |
Catalog # | orb153748 |
Price | |
Order / More Info | BCR Antibody from BIORBYT LTD. |
Product Specific References | n/a |
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