| 产品详情 |
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| Antigenic Specificity | BCR |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human, mouse, rat |
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| Isotype | n/a |
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| Format | immunogen affinity purified |
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| Size | 100µg |
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| Concentration | n/a |
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| Applications | ELISA, WB, IF, IHC, FC • WB 1:500 - 1:2000; IHC 1:50 - 1:100 |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Rabbit anti-BCR polyclonal antibody. A reciprocal translocation between chromosomes 22 and 9 produces the Philadelphia chromosome, which is often found in patients with chronic myelogenous leukemia. The chromosome 22 breakpoint for this translocation is located within the BCR gene. The translocation produces a fusion protein which is encoded by sequence from both BCR and ABL, the gene at the chromosome 9 breakpoint. Although the BCR-ABL fusion protein has been extensively studied, the function of the normal BCR gene product is not clear. The protein has serine/threonine kinase activity and is a GTPase-activating protein for p21rac. Two transcript variants encoding different isoforms have been found for this gene. |
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| Immunogen | breakpoint cluster region |
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| Other Names | BCR1, D22S11 |
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| Gene, Accession # | Gene ID: 613, UniProt: P11274 |
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| Catalog # | FNab00854 |
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| Price | |
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| Order / More Info | BCR Antibody from FINETEST |
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| Product Specific References | n/a |
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