产品详情 |
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Antigenic Specificity | CDH1 |
Clone | monoclonal |
Host Species | Mouse |
Reactive Species | human, mouse |
Isotype | IgG1κ |
Format | purified |
Size | 80 µl, 400 µl |
Concentration | n/a |
Applications | WB, IHC. RUO |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. CDH1 is involved in mechanisms regulating cell-cell adhesions, mobility and proliferation of epithelial cells. Has a potent invasive suppressor role. It is a ligand for integrin alpha-E/beta-7. E-Cad/CTF2 promotes non-amyloidogenic degradation of Abeta precursors. Has a strong inhibitory effect on APP C99 and C83 production. Purified His-tagged CDH1 protein was used to produced this monoclonal antibody. |
Immunogen | n/a |
Other Names | CADH1; cadherin 1; type 1; E-cadherin (epithelial) (ECAD); cadherin-1; CAM 120/80; E-cadherin; epithelial-cadherin; uvomorulin; CDH1; Arc-1; CD324; CDHE; ECAD; LCAM; UVO; E-Cad/CTF3; Epithelial cadherin; E-Cad/CTF1; E-Cad/CTF2; Um; E-cad; L-CAM; AA960649; E-Cadherin, |
Gene, Accession # | Accession: NP_004351.1, SwissProt: P12830 |
Catalog # | abx034792 |
Price | |
Order / More Info | CDH1 Antibody from ABBEXA |
Product Specific References | n/a |
产品资料 |
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