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                       | Product Name | A 410099.1 |  
                      
                       | Description | High affinity XIAP antagonist (Kd = 16 nM for the BIR3 domain of XIAP). Exhibits cytotoxicity in a wide range of cancer cell lines in vitro (EC50 = 13 nM in MDA-MB-231 cells). Also displays antitumor activity in a mouse breast cancer xenograft model. Enhances TRAIL-induced apoptosis in chronic lymphocytic leukemia (CLL) cells. Purity 98%. MW (observed): 505.09 |  
                      
                       | Size | 50 mg |  
                      
                       | Concentration | n/a |  
                      
                       | Applications | n/a |  
                      
                       | Other Names | N-Methyl-L-alanyl-(2S)-2-cyclohexylglycyl-N-[(1R)-1,2,3,4-tetrahydro-1-naphthalenyl]-L-prolinamide hydrochloride |  
                      
                       | Gene, Accession, CAS # | CAS: 762274-58-8 |  
                      
                       | Catalog # | 6470/50 |  
                      
                       | Price |  |  
                      
                       | Order / More Info | A 410099.1 from TOCRIS BIOSCIENCE
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                       | Product Specific References | PubMed: 19920200 |  
                      
                    
                  
            
            
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