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| Product Name | A 1070722 |
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| Description | Potent glycogen synthase kinase-3 (GSK-3) inhibitor (Ki = 0.6 nM for GSK-3α and GSK-3β). Displays high selectivity (> 50-fold) for GSK-3 over a panel of other kinases tested, including CDK family members. Decreases phosphorylation of microtubule-associated protein Tau in vitro; protects rat primary cortical neurons against β amyloid and glutamate challenge. Brain penetrant. Purity 99%. MW (observed): 362.31 |
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| Size | 50 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 1-(7-Methoxyquinolin-4-yl)-3-[6-(trifluoromethyl)pyridin-2-yl]urea |
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| Gene, Accession, CAS # | CAS: 1384424-80-9 |
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| Catalog # | 4431/50 |
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| Price | |
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| Order / More Info | A 1070722 from TOCRIS BIOSCIENCE
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| Product Specific References | n/a |
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