| 产品详情 |
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| Product Name | A83-01 |
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| Description | Purity >98% by NMR, TLC. A83-01 is a potent and selective ALK4, 5 and 7 inhibitor. IC50 = 45, 12 and 7.5 nM respectively. Prevents phosphorylation of Smad2/3 and growth inhibition induced by TGFb. Inhibits differentiation of rat induced pluripotent stem cells and increases clonal expansion efficiency. Together with AMI-5, A83-01 enabled Oct4-induced reprogramming of mouse embryonic fibroblasts. Cell permeable. Active in vivo. |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 3-(6-Methyl-2-pyridinyl)-N-phenyl-4-(4-quinolinyl)-1H-pyrazole-1-carbothioamide |
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| Gene, Accession, CAS # | CAS: 909910-43-6 |
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| Catalog # | LS-H14578 |
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| Order / More Info | A83-01 from LIFESPAN BIOSCIENCES INC. |
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| Product Specific References | n/a |
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| 产品资料 |
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