| 产品详情 |
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| Antigenic Specificity | ABL1 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human |
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| Isotype | n/a |
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| Format | affinity purified |
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| Size | 100 ul |
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| Concentration | n/a |
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| Applications | WB |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Rabbit polyclonal to ABL1.The ABL1 protooncogene encodes a cytoplasmic and nuclear protein tyrosine kinase that has beenimplicated in processes of cell differentiation, cell division, cell adhesion, and stress response. Activityof ABL1 protein is negatively regulated by its SH3 domain, and deletion of the SH3 domain turnsABL1 into an oncogene. The t(9;22) translocation results in the head-to-tail fusion of the BCR(MIM:151410) and ABL1 genes present in many cases of chronic myelogeneous leukemia. The DNAbindingactivity of the ubiquitously expressed ABL1 tyrosine kinase is regulated by CDC2-mediatedphosphorylation, suggesting a cell cycle function for ABL1 (provided by RefSeq). |
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| Immunogen | middle region of human ABL1 |
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| Other Names | ABL1,cabl oncogene 1,nonreceptor tyrosine kinase,ABL; JTK7; p150; cABL; vabl; bcr,abl,Abelsonmurine leukemia viral oncogene homolog 1 |
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| Gene, Accession # | UniProt: P00519 |
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| Catalog # | orb66952 |
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| Price | |
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| Order / More Info | ABL1 Antibody from BIORBYT LTD. |
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| Product Specific References | n/a |
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