| 产品详情 |
| Edit |   |
|---|
| Antigenic Specificity | CD40L/CD154 |
|---|
| Clone | LL2 |
|---|
| Host Species | Mouse |
|---|
| Reactive Species | human |
|---|
| Isotype | IgG1 |
|---|
| Format | purified |
|---|
| Size | 100µg/50µg |
|---|
| Concentration | n/a |
|---|
| Applications | Flow cytometry, IF, T cell activation, block CD40-CD40L interaction, ELISA for sCD154 detection |
|---|
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
|---|
| Description | CD40 ligand also known as TRAP, gp39, TNFSF5, is a 261 amino acid type II transmembrane glycoprotein belonging to the TNF superfamily. CD40 ligand is expressed predominantly on activated CD4+ T cells and is also found on other cell types, including NK cells, mast cells, basophils and eosinophils. Genetic alterations in the CD40L results in the absence of a functional molecule on activated T cells and are responsible for the occurrence of X-linked hyper-IgM syndrome. LL48 clone is a CD40L neutralizing antibody and plays an important role in costimulatory interactions between T and B lymphocytes, and antigen-presenting cells and lymphocytes regulating the immune system at multiple levels. (Tong AW et al, 2001; Clin. Canc. Res., 7:691-703; Hill A. et al, 1993; Nature, 361:494-503; Peguet-Navarro J. et al, 1995; J. Immunol., 155:4241-4247) |
|---|
| Immunogen | n/a |
|---|
| Other Names | n/a |
|---|
| Gene, Accession # | n/a |
|---|
| Catalog # | DDX0141 |
|---|
| Price | |
|---|
| Order / More Info | CD40L/CD154 Antibody from DENDRITICS SAS |
|---|
| Product Specific References | n/a |
|---|
| 产品资料 |
|
|