产品详情 |
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Antigenic Specificity | NOTCH4 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | affinity purified |
Size | 100 ul |
Concentration | n/a |
Applications | WB |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Rabbit polyclonal to NOTCH4.Neurogenic locus notch homolog protein 4 (NOTCH4) is a single pass membrane protein that belongsto the NOTCH family. NOTCH4 functions as a receptor for membrane-bound ligands Jagged1,Jagged2 and Delta1 to regulate cell-fate determination. NOTCH4 is cleaved upon ligand activationand the notch intracellular domain (NICD) is released, which forms a transcriptional activator complexwith RBPJ/RBPSUH to activate genes of the enhancer of split locus. It affects the implementation ofdifferentiation, proliferation and apoptotic programs. |
Immunogen | C-terminal region of human NOTCH4 |
Other Names | NOTCH4,Neurogenic locus notch homolog protein 4,Notch 4,hNotch4,INT3 |
Gene, Accession # | UniProt: Q99466 |
Catalog # | orb67113 |
Price | |
Order / More Info | NOTCH4 Antibody from BIORBYT LTD. |
Product Specific References | n/a |
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