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Product Name | Human IFN Gamma / Interferon Gamma Protein (Recombinant) |
Description | Purity >95% by SDS-PAGE, MW: 17 kDa. Human Interferon gamma (hIFN-gamma) is amacrophage-activating factor and the lone member of Interferon type II.The active form of IFN-gamma is an antiparallel dimer that interacts with the receptor IFN-gammaR1 and sets off IFN-gamma/JAK/STAT pathway. IFN-gamma signaling does diverse biological functions primarily related to host defense and immune regulation, including antiviral and antibacterial defense, apoptosis, inflammation, and innate and acquired immunity. While IFN-gamma-induced inflammatory cascade summons a variety of immune-related cell types, such as macrophages, natural killer (NK) cells and cytotoxic T lymphocytes (CTLs), IFN-gamma is also implicated in resistance to NK cell and CTL responses and in immune escape in a variety of cancers. Recombinant human Interferon gamma (rhIFN-gamma) produced in E. coli is a non-glycosylated polypeptide chain of 144 amino acids. A fully biologically active molecule, rhIFN-gamma has a molecular mass of 17 kDa analyzed by reducing SDS-PAGE and is obtained by refolding and chromatographic techniques. |
Size | n/a |
Concentration | n/a |
Applications | n/a |
Other Names | IFNG, IFG, Immune interferon, IFI, Interferon gamma, IFN-gamma, Interferon, gamma |
Gene, Accession, CAS # | IFNG, Gene ID: 3458 |
Catalog # | LS-G27043 |
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Order / More Info | Human IFN Gamma / Interferon Gamma Protein (Recombinant) from LIFESPAN BIOSCIENCES INC. |
Product Specific References | n/a |
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