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Product Name | gamma-Interferon-Induced Monokine (CXCL9) (Active) protein |
Description | CXCL9, a member of the α subfamily of chemokines that lack the ELR domain, was initially identified as a lymphokine-activated gene in mouse macrophages. The CXCL9 gene is induced in macrophages and in primary glial cells of the central nervous system specifically in response to IFN-γ. CXCL9 has been shown to be a chemoattractant for activated T-lymphocytes and TIL but not for neutrophils or monocytes. The human CXCL9 cDNA encodes a 125 amino acid residue precursor protein with a 22 amino acid residue signal peptide that is cleaved to yield a 103 amino acid residue mature protein. CXCL9 has an extended carboxy-terminus containing greater than 50% basic amino acid residues and is larger than most other chemokines. A chemokine receptor (CXCR3) specific for CXCL9 and IP-10 has recently been cloned and shown to be highly expressed in IL-2-activated T-lymphocytes. Synonym: MIG/CXCL9, Human. Formulation: Lyophilized from a 0.2µm filtered concentrated solution in 20mM PB, pH 7.4, 50mM NaCl. |
Size | 20 µg |
Concentration | n/a |
Applications | n/a |
Other Names | CMK|Humig|MIG|SCYB9|crg-10|BB139920|Mig|MuMIG|Scyb9 |
Gene, Accession, CAS # | Gene ID: 4283 |
Catalog # | ABIN988152 |
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Order / More Info | gamma-Interferon-Induced Monokine (CXCL9) (Active) protein from ANTIBODIES-ONLINE GmbH |
Product Specific References | n/a |
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