| Edit |   |
|---|
| Antigenic Specificity | Apaf-1 |
|---|
| Clone | polyclonal |
|---|
| Host Species | Rabbit |
|---|
| Reactive Species | human and mouse |
|---|
| Isotype | n/a |
|---|
| Format | unconjugated |
|---|
| Size | 1 ea |
|---|
| Concentration | n/a |
|---|
| Applications | Western Blot |
|---|
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
|---|
| Description | Immunogen: Synthetic peptide from an N-terminal region of human Apaf-1 • Host: Rabbit • Species Reactivity: (+) Human and mouse • Application: WB • Apaf-1 binds to cytochrome c (Apaf-2) and caspase-9 (Apaf-3), which leads to caspase-9 activation. Activated caspase-9 in turn cleaves and activates caspase-3, one of the key proteases responsible for the proteolytic cleavage of many key proteins in apoptosis. It can also associate with caspase-4 and -8. |
|---|
| Immunogen | Synthetic peptide from an N-terminal region of human Apaf-1 |
|---|
| Other Names | Apoptosis Protease-Activating Factor 1 |
|---|
| Gene, Accession # | n/a |
|---|
| Catalog # | 160780-100 |
|---|
| Price | |
|---|
| Order / More Info | Apaf-1 Antibody from CAYMAN CHEMICAL COMPANY |
|---|
| Product Specific References | n/a |
|---|