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| Product Name | Cell Division Cycle 73, Paf1/RNA Polymerase II Complex Component, Homolog (S. Cerevisiae) (CDC73) (AA 2-260) protein |
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| Description | Recombinant Human Parafibromin is produced by our E. coli expression system. The target protein is expressed with sequence (Ala2-Glu260) of Human CDC73 fused with a 6His tag at the N-terminus. Parafibromin is expressed in the adrenal and parathyroid glands, kidney, and heart. As a tumor supressor, Parafibromin may be involved in transcriptional and post-transcriptional control pathways, also through the regulation of cyclin D1/PRAD1 expression, involved the cell cycle progression. Parafibromin is a component of the the PAF protein complex and interacts with a Set1-like complex that has histone methyltransferase activity and methylates histone H3. Defects in Parafibromin can cause hyperparathyroidism-jaw tumor syndrome, familial isolated hyperparathyroidism, and parathyroid carcinoma. |
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| Size | 500 µg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | CG11990|Cdc73|Dmel\\CG11990|Hyx|hyx/CDC73|cdc37|MGC52623|hrpt2|MGC108428|cdc73|LOC100222932|C1orf28|HPTJT|HRPT2|HYX|Hrpt2|8430414L16Rik|BC027756|C130030P16Rik|C81219|zgc:63956 |
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| Gene, Accession, CAS # | Gene ID: 79577 |
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| Catalog # | ABIN1691838 |
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| Order / More Info | Cell Division Cycle 73, Paf1/RNA Polymerase II Complex Component, Homolog (S. Cerevisiae) (CDC73) (AA 2-260) protein from ANTIBODIES-ONLINE GmbH |
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| Product Specific References | n/a |
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