产品名称 MARCH1 Antibody from CREATIVE DIAGNOSTICS
产品货号 CABT-BL2321
产品价格 现货询价,电话:010-67529703
产品规格 n/a
产品品牌 CREATIVE DIAGNOSTICS
产品概述
产品详情
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Antigenic SpecificityMARCH1
CloneMAAG6019
Host SpeciesMouse
Reactive Specieshuman
IsotypeIgG2a
Formatunconjugated
Sizen/a
Concentrationn/a
ApplicationsELISA
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DescriptionMouse Anti-Human MARCH1 monoclonal antibody for ELISA. MARCH1 is a member of the MARCH family of membrane-bound E3 ubiquitin ligases (EC 6.3.2.19). MARCH proteins add ubiquitin (see MIM 191339) to target lysines in substrate proteins, thereby signaling their vesicular transport between membrane compartments. MARCH1 downregulates the surface expression of major histocompatibility complex (MHC) class II molecules (see MIM 142880) and other glycoproteins by directing them to the late endosomal/lysosomal compartment (Bartee et al., 2004 [PubMed 14722266]; Thibodeau et al., 2008 [PubMed 18389477]; De Gassart et al., 2008 [PubMed 18305173]).[supplied by OMIM, Mar 2010]
ImmunogenRecombinant Protein
Other Namesn/a
Gene, Accession #Gene ID: 55016, UniProt: A8K0Z6
Catalog #CABT-BL2321
Price
Order / More InfoMARCH1 Antibody from CREATIVE DIAGNOSTICS
Product Specific Referencesn/a
产品资料