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Product Name | Cathepsin S (CTSS) (C-Term) protein |
Description | Recombinant Human Cathepsin S is produced with our mammalian expression system in human cells. The target protein is expressed with the full length sequence of Human CTSS fused with a polyhistidine tag at the C-terminus. Cathepsin S is a lysosomal enzyme that belongs to the papain family of cysteine proteases. This protein is expressed by antigen presenting cells including macrophages, B-lymphocytes, dendritic cells and microglia. Moreover, cathepsin S is expressed in some epithelial cells. Compared with the abundant cathepsins B, L and H, cathepsin S shows a restricted tissue distribution, with highest levels in spleen, heart, and lung. In addition, evidences indicated that cathepsin S generates A β from amyloidogenic fragments of β APP in the endosomal/lysosomal compartment, and is implicated in the pathogenesis of Alzheimer's disease (AD) and Down Syndrome (DS). |
Size | 1 mg |
Concentration | n/a |
Applications | n/a |
Other Names | ctss-a|MGC69026|ctss-b|MGC80097|ctss.1|CTSS|ctss|cats |
Gene, Accession, CAS # | Gene ID: 1520 |
Catalog # | ABIN1096246 |
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Order / More Info | Cathepsin S (CTSS) (C-Term) protein from ANTIBODIES-ONLINE GmbH |
Product Specific References | n/a |
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