产品名称 MJ33 (lithium salt) from LIFESPAN BIOSCIENCES INC.
产品货号 LS-H8710
产品价格 现货询价,电话:010-67529703
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产品品牌 LIFESPAN BIOSCIENCES INC.
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Product NameMJ33 (lithium salt)
DescriptionPurity >95%. Peroxiredoxin-6 (Prdx6) is a bifunctional enzyme that has both non-selenium glutathione peroxidase (Gpx) and phospholipase A2 (PLA2 ) activities. Its PLA2 activity is calcium-independent, functions optimally in acidic (pH = 4) conditions, and facilitates the intracellular processing of surfactant lipids, including dipalmitoylphosphatidylcholine (DPPC). MJ33 is a selective, reversible inhibitor of the acidic, calcium-independent (ai)PLA2 activity of Prdx6, with optimal inhibition achieved at an MJ33 concentration of 3 mol%. It blocks the degradation of DPPC in both whole lung and isolated alveolar type II epithelial cells. MJ33 has been used to examine the role of Prdx6 PLA2 activity in the activation of type 2 NADPH oxidase and in the regulation of Prdx6 PLA2 activity by phosphorylation.
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Other Namesmono[1-[(hexadecyloxy)methyl]-2-(2,2,2-trifluoroethoxy)ethyl] monomethyl ester phosphoric acid, monolithium salt
Gene, Accession, CAS #CAS: 1007476-63-2
Catalog #LS-H8710
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Order / More InfoMJ33 (lithium salt) from LIFESPAN BIOSCIENCES INC.
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