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| Product Name | CD40 Molecule, TNF Receptor Superfamily Member 5 (CD40) (AA 21-193) (Active) protein (Fc Tag) |
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| Description | CD40 belongs to the TNF-receptor superfamily and is essential in mediating a broad variety of immune and inflammatory responses including T cell-dependent immunoglobulin class switching, memory B cell development and germinal center formation. The interaction of CD40-CD40L is necessary for amyloid-beta-induced microglial activation, and thus is thought to be an early event in Alzheimer disease pathogenesis. CD40 is constitutively expressed by antigen presenting cells, including dendritic cells, B cells and macrophages. Consistent with its widespread expression on normal cells, CD40 is also expressed on a wide range of tumor cells, including non-Hodgkin's and Hodgkin's lymphomas, myeloma and some carcinomas including nasopharynx, bladder, cervix, kidney and ovary. |
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| Size | 3 x 50 µg |
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| Concentration | n/a |
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| Applications | SDS-PAGE (SDS) |
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| Other Names | AI326936|Bp50|GP39|HIGM1|IGM|IMD3|T-BAM|TRAP|Tnfrsf5|p50|CDW40|TNFRSF5|TNFSF5|2310042E05Rik|C130077D06Rik|C87049|DCTN-50|GMP23-48K|RBP50 |
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| Gene, Accession, CAS # | Gene ID: 958, 21939 |
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| Catalog # | ABIN1344136 |
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| Order / More Info | CD40 Molecule, TNF Receptor Superfamily Member 5 (CD40) (AA 21-193) (Active) protein (Fc Tag) from ANTIBODIES-ONLINE GmbH |
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| Product Specific References | n/a |
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