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| Product Name | HIV-1 Nef 3-190 peptide |
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| Description | HIV-1 Nef (residues 3-190) protein.The protein contains the fragment of HIV-1 Nef protein,amino acids 3-190, the molecular weight is 20 kDa. TheHIV-1 nef is fused to beta-galactosidase (114 kDa) at theN-terminus.The protein was purified by proprietary chromatographictechnique.HIV belongs to the retrovirus family, distinguished by possession of a viral reverse transcriptase that transcribes viral RNA into DNA which is integrated into the host-cellgenome.Human immunodeficiency virus type 1 (HIV-1) Nef is amembrane-associated protein that is produced at the earliest stage of viral gene expression and is a component ofviral particles. Nef has been demonstrated to bind anddownregulate cell-surface receptors CD4 and MHC I. Inaddition, Nef has been reported to have diverse effectson cellular signal transduction pathways.It interacts with various cellular protein kinases and actsboth as a kinase substrate and as a modulator of kinaseactivity. Purity >95% by SDS-PAGE and HPLC |
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| Size | 100 ug |
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| Concentration | n/a |
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| Applications | ELISA, WB |
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| Other Names | n/a |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | orb73426 |
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| Order / More Info | HIV-1 Nef 3-190 peptide from BIORBYT LTD. |
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| Product Specific References | n/a |
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