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| Product Name | Human Glial growth factor (GGF2) Recombinant |
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| Description | MW: 70,392 Da. Purity >95%, as determined by SDS-PAGE and HPLC. Neuregulins (NDF, heregulin, GGF ARIA, or SMDF) are EGF- like growth and differentiation factors that signal through tyrosine kinase receptors of the ErbB family.The ErbB2 and ErbB4 receptors cooperate in transmission of neuregulin-1 signals in the heart, whereas ErbB2 and ErbB3 cooperate in neural crest cells. |
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| Size | 0.02 mg, 0.05 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | [Human Glial growth factor (GGF2) Recombinant ; egf; ggf2; nrg1; nrg-1; glial; heregulin; hrg] |
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| Gene, Accession, CAS # | GGF2, Gene ID: 3084, Accession: NP_001153467.1 |
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| Catalog # | MBS553231 |
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| Order / More Info | Human Glial growth factor (GGF2) Recombinant from MYBIOSOURCE INC. |
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| Product Specific References | • hypertrophic neuropathies and malignant peripheral nerve sheath tumors in transgenic mice overexpressing Glial Growth Factor 3 in myelinating schwann cells .J. Neurosci., Aug 2003; 23: 7269. • in vivo analysis of schwann cell programmed cell death in the embryonic chick: regulation by axons and Glial Growth Factor .J. Neurosci., Jun 2002; 22: 4509. • Glial Growth Factor/neuregulin inhibits schwann cell myelination and induces demyelination .J. Cell Biol., Mar 2001; 152: 1289 - 1 |
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