| 产品详情 |
| Edit |   |
|---|
| Antigenic Specificity | Caspase 3 |
|---|
| Clone | polyclonal |
|---|
| Host Species | Rabbit |
|---|
| Reactive Species | human |
|---|
| Isotype | n/a |
|---|
| Format | purified |
|---|
| Size | 80 µl, 400 µl |
|---|
| Concentration | n/a |
|---|
| Applications | WB, IHC, FCM. RUO |
|---|
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
|---|
| Description | CASP3 is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein cleaves and activates caspases 6, 7 and 9, and the protein itself is processed by caspases 8, 9 and 10. It is the predominant caspase involved in the cleavage of amyloid-beta 4A precursor protein, which is associated with neuronal death in Alzheimer's disease. This Caspase-3 (CASP3) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 60-90 amino acids from the Central region of human Caspase-3 (CASP3). |
|---|
| Immunogen | Human Caspase-3. |
|---|
| Other Names | Apopain precursor; CASP-3; CPP-32; CPP32; Caspase-3; Cysteine protease CPP32; ICE3; SCA-1; SREBP cleavage activity 1; Yama protein; Apopain; CASP3; caspase 3; apoptosis-related cysteine peptidase; apoptosis-related cysteine protease; Caspase-3 subunit p12; Caspase-3 subunit p17; CPP32B; PARP cleavage protease; procaspase3; Protein Yama; Yama; Cysteine Protease Cpp32Protein Yama; caspase 3, apoptosis-related cysteine protease; HGNC:1504; caspase 3, apoptosis-related cysteine peptidase; SCA1; Apoptain; Cysteinyl Aspartate Specific Proteinases 3 |
|---|
| Gene, Accession # | SwissProt: P42574 |
|---|
| Catalog # | abx033479 |
|---|
| Price | |
|---|
| Order / More Info | Caspase 3 Antibody from ABBEXA |
|---|
| Product Specific References | n/a |
|---|
| 产品资料 |
|
|