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| Antigenic Specificity | n-Myc/MYCN |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human, rat (predicted: bovine) |
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| Isotype | n/a |
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| Format | immunogen affinity purified |
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| Size | 100ug (sample available) |
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| Concentration | 500ug/ml. |
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| Applications | WB |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Rabbit IgG polyclonal Picoband™ antibody for N-myc proto-oncogene protein(MYCN) detection. Tested with WB in Human;Rat. No cross reactivity with other proteins. N-myc proto-oncogene protein, also known as N-Myc or basic helix-loop-helix protein 37 (bHLHe37), is a protein that in humans is encoded by the MYCN gene. This gene is a member of the MYC family and encodes a protein with a basic helix-loop-helix (bHLH) domain. And this protein is located in the nucleus and must dimerize with another bHLH protein in order to bind DNA. Amplification of this gene is associated with a variety of tumors, most notably neuroblastomas. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. |
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| Immunogen | A synthetic peptide corresponding to a sequence at the C-terminus of human n-Myc (428-464aa EYVHSLQAEEHQLLLEKEKLQARQQQLLKKIEHARTC), different from the related mouse and rat sequences by two amino acids. |
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| Other Names | N-myc proto-oncogene protein;Class E basic helix-loop-helix protein 37;bHLHe37;MYCN;BHLHE37, NMYC; |
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| Gene, Accession # | MYCN, UniProt: P04198 |
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| Catalog # | PB9728 |
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| Price | |
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| Order / More Info | n-Myc/MYCN Antibody from BOSTER BIO |
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| Product Specific References | n/a |
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