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| Product Name | BAR501 |
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| Description | A selective GP-BAR1 agonist (EC50 = 1 µM); reduces hepatic perfusion pressure and counteracts norepinephrine-induced vasoconstriction in naive rats; protects against development of endothelial dysfunction by increasing CSE expression and activity and reducing ET-1 gene expression in rat model of cirrhosis; increases Akt-dependent phosphorylation of CSE and eNOS and inhibits ET-1 transcription in vitro; reduces trinitrobenzenesulfonic acid-induced colitis in mice in a dose-dependent manner |
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| Size | 25 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | BAR-501 GPBAR1 GPBAR-1 g ET1 M-1 M-2 NE antiinflammatory |
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| Gene, Accession, CAS # | CAS: 1632118-69-4 |
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| Catalog # | 22460-25 |
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| Price | |
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| Order / More Info | BAR501 from CAYMAN CHEMICAL COMPANY |
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| Product Specific References | n/a |
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| 产品资料 |
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