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| Antigenic Specificity | Neurotrophic Tyrosine Kinase, Receptor, Type 1 (NTRK1) (aa 33-423) |
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| Clone | 6B2 |
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| Host Species | Mouse |
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| Reactive Species | human |
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| Isotype | IgG1 |
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| Format | ascites |
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| Size | 100 µL |
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| Concentration | n/a |
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| Applications | ELISA,Western Blotting (WB),Immunocytochemistry (ICC) |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | TrkA, also known as NTRK1, MTC, TRK, TRK1. It is a member of the neurotrophic tyrosine kinase receptor (NTKR) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. The presence of this kinase leads to cell differentiation and may play a role in specifying sensory neuron subtypes. Mutations in this gene have been associated with congenital insensitivity to pain, anhidrosis, self-mutilating behavior, mental retardation and cancer. Alternate transcriptional splice variants of this gene have been found, but only three have been characterized to date. |
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| Immunogen | Purified recombinant extracellular fragment of human TrkA (AA 33-423) fused with hIgGFc tag expressed in HEK293 cell line. |
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| Other Names | trk|trka|TRKA|MTC|TRK|TRK1|Trk-A|p140-TrkA|C80751|Tkr|TrkA|Trk|CTRKA|trkA|CAPM1|CFTD|NEM1|OK/SW-cl.5|TM-5|TM3|TM30|TM30nm|TM5|TPMsk3|hscp30 |
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| Gene, Accession # | Gene ID: 4914 |
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| Catalog # | ABIN969444 |
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| Order / More Info | Neurotrophic Tyrosine Kinase, Receptor, Type 1 (NTRK1) (aa 33-423) Antibody from ANTIBODIES-ONLINE GmbH |
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| Product Specific References | PubMed: 18419753, 18678285 |
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