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Product Name | Necrosulfonamide |
Description | Necrosulfonamide is a potent necroptosis inhibitor. It blocks mixed lineage kinase domain-like protein (MLKL), a critical substrate of receptor-interacting serine-threonine kinase 3 (RIP3) during necrosis. Prevents MLKL-RIP1-RIP3 necrosome complex from interacting with downstream necrosis effectors. Unlike Necrostatin-1 (Cat. No. 1864), NSA does not inhibit the necrosis-induced RIP1 and RIP3 interactions. MW: 461.47. Purity ≥98% by HPLC |
Size | 10 mg |
Concentration | n/a |
Applications | n/a |
Other Names | (2E)-N-[4-[[(3-Methoxy-2-pyrazinyl)amino]sulfonyl]phenyl]-3-(5-nitro-2-thienyl)-2-propenamide; NSA |
Gene, Accession, CAS # | CAS: 1360614-48-7 |
Catalog # | 9635-10 |
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Order / More Info | Necrosulfonamide from BIOVISION, INC. |
Product Specific References | n/a |
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