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Product Name | ML-277 |
Description | Purity 98%. Potassium (K+) channels are categorized by their mode of activation and the number of transmembrane segments. ML-277 is a potent activator of KCNQ1 channels (EC50 = 260 nM). The EC50 value of this compound at the related channels KCNQ2, KCNQ4, and hERG exceeds 30 uM. ML-277 potentiates both homomultimeric KCNQ1 channels and unsaturated heteromultimeric (KCNQ1/KCNE1) channels in model cardiomyocytes and augments delayed rectifier K+ current in cultured human cardiomyocytes |
Size | 5 mg, 1ml/10mM (In DMSO), 10 mg, 25 mg, 50 mg |
Concentration | n/a |
Applications | n/a |
Other Names | n/a |
Gene, Accession, CAS # | CAS: 1401242-74-7 |
Catalog # | MBS578345 |
Price | |
Order / More Info | ML-277 from MYBIOSOURCE INC. |
Product Specific References | n/a |
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