| 产品详情 |
| Edit |   |
|---|
| Product Name | ML-240 |
|---|
| Description | MW: 396.44. Purity ≥98% by HPLC. ML-240 is an ATP-competitive inhibitor of the D2 domain of the p97 ATPase (IC50 = 110 nM). It disrupts the endoplasmic reticulum-associated degradation and autophagy pathways; preventing the degradation of p97-dependent proteasome substrates (IC50 = 0.9 uM) and causing accumulation of ubiquitin conjugates in nuclear membrane and cytosolic compartments at 5-10 uM. ML-240 has also been shown to block proliferation of HCT15 and SW403 colon cancer cell lines (GIs |
|---|
| Size | 5 mg, 25 mg |
|---|
| Concentration | n/a |
|---|
| Applications | n/a |
|---|
| Other Names | [2- (2-Amino-1H-benzimidazole-1-yl)-8-methoxy-N- (phenylmethyl)-4-quinazolinamine] |
|---|
| Gene, Accession, CAS # | CAS: 1346527-98-7 |
|---|
| Catalog # | MBS846285 |
|---|
| Price | |
|---|
| Order / More Info | ML-240 from MYBIOSOURCE INC. |
|---|
| Product Specific References | n/a |
|---|
| 产品资料 |
|
|