| 产品详情 |
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| Product Name | PACAP (6-27) (human, chicken, mouse, ovine, porcine, rat) (trifluoroacetate salt) |
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| Description | A PACAP receptor antagonist (IC50s = 1,500, 600, and 300 nM, respectively, for rat PAC1, rat VPAC1, and human VPAC2 recombinant receptors); binds to PACAP receptors on SH-SY5Y and SK-N-MC human neuroblastoma and T47D human breast cancer cells (IC50s = 24.5, 106, and 105 nM, respectively); inhibits PACAP (1-38)-stimulated cAMP accumulation in SH-SY5Y, SK-N-MC, and T47D cells (Kis = 457, 102, and 283 nM, respectively); inhibits vasodilation of pial arterioles induced by PACAP (1-27) and PACAP (1-38) in newborn pigs (10 µM); inhibits PACAP (1-27)-stimulated increases in plasma insulin and glucagon levels and pancreatic venous blood flow in dogs (500 µg administered locally to the pancreas), |
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| Size | 500 µg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | Pituitary Adenylate Cyclase-activating Peptide (6-27) |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | 24771-500 |
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| Order / More Info | PACAP (6-27) (human, chicken, mouse, ovine, porcine, rat) (trifluoroacetate salt) from CAYMAN CHEMICAL COMPANY |
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| Product Specific References | n/a |
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