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| Product Name | 2-Deoxy-D-Glucose |
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| Description | 2-Deoxy-D-Glucose is a glucose analog that has long been known to act as a competitive inhibitor of glucose metabolism. Upon transport into the cells, 2-DG is phosphorylated by hexokinase to 2-DG-P. However, unlike G-6-P, 2-DG-P cannot be further metabolized by phosphohexose isomerase, which converts G-6-P to fructose-6-phosphate. 2-Deoxyglucose-P is trapped and accumulated in the cells, leading to inhibition of glycolysis mainly at the step of phosphorylation of glucose by hexokinase. Inhibition of this rate-limiting step by 2-DG causes a depletion of cellular ATP, leading to blockage of cell cycle progression and cell death in vitro. MW: 164.16. Purity ≥98% GC |
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| Size | 100 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 2-Deoxy-D-arabinohexose, 2-Deoxyglucose |
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| Gene, Accession, CAS # | CAS: 154-17-6 |
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| Catalog # | B1048-100 |
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| Order / More Info | 2-Deoxy-D-Glucose from BIOVISION, INC. |
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| Product Specific References | n/a |
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