| 产品详情 |
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| Product Name | OF-1 |
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| Description | Purity >98%. OF-1 is a chemical probe for the bromodomains of the Bromodomain and PHD Finger-containing (BRPF) family of proteins. It binds BRPF1B, BRPF2, and BRPF3 with Kd values of 0.1, 0.5, and 2.4 µM, respectively, as determined by isothermal titration calorimetry. OF-1 increases thermal stability of full length BRPF1B at 1 µM, in the cellular thermal shift assay. It also demonstrates accelerated fluorescence recovery after photobleaching (FRAP) at 5 µM in the BRPF2 FRAP assay. OF-1 shows modest general cytotoxicity. See the Structural Genomics Consortium (SGC) website for further information. |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 4-bromo-N-(2,3-dihydro-6-methoxy-1,3-dimethyl-2-oxo-1H-benzimidazol-5-yl)-2-methyl-benzenesulfonamide |
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| Gene, Accession, CAS # | CAS: 919973-83-4 |
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| Catalog # | LS-H9147 |
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| Price | |
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| Order / More Info | OF-1 from LIFESPAN BIOSCIENCES INC. |
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| Product Specific References | n/a |
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| 产品资料 |
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