| 产品详情 |
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| Product Name | Hexokinase (HK) Inhibitor Screening Kit (Colorimetric) |
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| Description | Hexokinases (HK) play an important role in glucose metabolism. Hexokinases phosphorylate glucose and generate glucose-6-phosphate for glycolysis. Hexokinases have four isoforms (HK-I, II, III and IV). HK-I, HK-II and HK-III have low Km, while HK-IV has 100 fold high Km. Hexokinase deficiency leads to severe human diseases such as X-linked muscular dystrophy and a rare autosomal recessive hemolytic anemia. On the other hand, increased hexokinase activity is detected in various tumors and is associated with metastasis. In BioVision's Hexokinase Inhibitor Screening kit, glucose is converted to glucose-6-phosphate by hexokinase; the glucose-6-phosphate is oxidized by glucose-6-phosphate dehydrogenase to form NADH, which reduces a colorless prob |
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| Size | 100 assays |
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| Concentration | n/a |
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| Applications | • Screening/characterizing/studying potential inhibitors of Hexokinase |
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| Other Names | n/a |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | K828-100 |
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| Order / More Info | Hexokinase (HK) Inhibitor Screening Kit (Colorimetric) from BIOVISION, INC. |
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| Product Specific References | n/a |
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