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Product Name | N-nonanoyl-L-Homoserine lactone |
Description | Purity >98%. Quorum sensing is a regulatory system used by bacteria for controlling gene expression in response to increasing cell density. This regulatory process manifests itself with a variety of phenotypes including biofilm formation and virulence factor production. Coordinated gene expression is achieved by the production, release, and detection of small diffusible signal molecules called autoinducers. The N-acylated homoserine lactones (AHLs) comprise one such class of autoinducers, each of which generally consists of a fatty acid coupled with homoserine lactone (HSL). Regulation of bacterial quorum sensing signaling systems to inhibit pathogenesis represents a new approach to antimicrobial therapy in the treatment of infectious diseases. AHLs vary in acyl group length (C4 -C18 ), in the substitution of C3 (hydrogen, hydroxyl, or oxo group), and in the presence or absence of one or more carbon-carbon double bonds in the fatty acid chain. These differences confer signal specificity through the affinity of transcriptional regulators of the LuxR family. C9 -HSL is a rare odd-numbered acyl carbon chain produced by wild-type Erwinia carotovora strain SCC 3193 grown in the nutrient-rich Luria-Bertani Broth (LB) medium. |
Size | n/a |
Concentration | n/a |
Applications | n/a |
Other Names | N-[(3S)-tetrahydro-2-oxo-3-furanyl]-nonanamide, C9-HSL |
Gene, Accession, CAS # | CAS: 177158-21-3 |
Catalog # | LS-H9028 |
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Order / More Info | N-nonanoyl-L-Homoserine lactone from LIFESPAN BIOSCIENCES INC. |
Product Specific References | n/a |
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