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Product Name | Formiminotransferase Cyclodeaminase (FTCD) protein (Biotin) |
Description | Formiminotransferase cyclodeaminase is an enzyme which catalyzes the conversion of formiminoglutamateand tetrahydrofolateinto formiminotetrahydrofolateand glutamate.Formiminotransferase cyclodeaminase, a bifunctional enzyme of tetrahydrofolate synthesis, is the target antigen of anti-LC1 (liver cytosol antigen type 1) autoantibodies. Presence of LC1 autoantibodies is a marker for type 2 autoimmune hepatitis (for which anti-LKM 1/cytochrome P450 2D6 autoantibodies are a further marker).Serum LC1 autoantibody concentrations appear to fluctuate in parallel with aminotransferase levels, a particularly intriguing observation that suggests a possible role of LC1 autoreactivity in the pathogenic mechanism leading to hepatocyte injury Synonyms: Formiminotransferase-cyclodeaminase, FTCD, LCHC1, LC-1 |
Size | 5 µg |
Concentration | n/a |
Applications | Transfected Cell Culture (TCC) |
Other Names | FTCD|wu:fp37b11|LCHC1|zgc:63647 |
Gene, Accession, CAS # | Gene ID: 10841 |
Catalog # | ABIN805460 |
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Order / More Info | Formiminotransferase Cyclodeaminase (FTCD) protein (Biotin) from ANTIBODIES-ONLINE GmbH |
Product Specific References | n/a |
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